State of the art MALDI-TOF instrument for high sensitivity measurement of limited sample quantity (routinely low fmol amounts). 2 kHz laser repetition rate (1 kHz in TOF/TOF mode) enables very rapid data acquisition at high resolution and mass accuracy. Smartbeam II laser technology enables focus to 10 μm for high resolution spatial imaging applications. Applications include rapid top-down sequence confirmation of biopharmaceuticals, high speed tissue imaging for biodistribution and biomarker discovery, proteomics and glycoproteomics. LC-MALDI capabilities for high sensitivity measurement and offline interrogation of samples at greater depth than conventional online LC-MS proteomics.

Capabilities

✓Matrix-assisted laser desorption/ionization
✓Time-of-flight mass spectrometry
✓High sensitivity (low fmol detection)
✓2 kHz laser repetition rate
✓10 μm spatial resolution imaging
✓Biopharmaceutical sequencing
✓Tissue imaging
✓Biodistribution studies
✓Biomarker discovery
✓LC-MALDI capabilities

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Specifications

model	UltrafleXtreme
technique	MALDI-TOF/TOF
laser rate	2 kHz (1 kHz TOF/TOF)
spatial resolution	10 μm
sensitivity	Low fmol amounts